Write up of 'Cameroon Case Study' Coursework Example | Topics and Well Written Essays - 1250 words

Write up of 'Cameroon Case Study' - Coursework Example However, there are other sickle cell anaemia screening tests unavailable to test sickle cell anaemia in the small laboratory at the Mbetta Health Center. The tests require high cost, a lot of time, and they are by the high temperature and humidity. On the first day in Cameroon at Mbetta Village, the nursing staff referred to me a case of a boy aged 4 years. The boy was clearly unwell; he presented fever, headache, fatigue, pain in the arms and legs. On physical examination by a nurse, the boy`s blood pressure was in a normal range and he had no palpable lymph node. However, the higher left hand abdominal quadrant palpation, auscultation, and percussion signified an enlarged spleen. The nurse noted the boy`s mucus to be pale in colour on examination and the sclera portrayed some elements of Icterus. With no any other abnormal physical signs observed from the boy, the nurse took a venous blood sample and put it into anticoagulant to assist in carrying out a laboratory investigation of the disease. Sickle cell anaemia affects bones, lungs, abdomen, joints, limbs, and lungs (Ohene-Frempong 2006). For instance, pain, swelling, and fever occur when sickle cells block limb veins (Center for children with Special Needs 2006). When spleen traps many red blood cells a mechanism meant to trap the abnormal red blood cells, it enlarges (Maakaron, E. J. n.d.). Lastly, life-threatening cases of sickle cell anaemia occur when red blood cells are trapped in the lung vein to cause Acute Chest Syndrome, which may damage vein in the lungs. It is detected through abnormal breathing and normal blood pressure (Ohene-Frempong 2006). The laboratory in Mbetta village is small and equipped as a basic haematology laboratory. It contains microscope, slides, cover slips, and various stains like Romanowsky stain and immersion oil. It is also equipped with haematocrit centrifuge, glass capillaries, an electrophoresis tank, and a power pack. A

Coherent Diffraction Imaging Essay Example | Topics and Well Written Essays - 5000 words

Coherent Diffraction Imaging - Essay Example The purpose of this paper is to give a general overview of the phase problem; to discuss existing iterative phase reconstruction algorithms, aimed to solve the problem; to consider their peculiar properties and differences. In addition, the recent developments in coherent diffraction imaging are reviewed, with an emphasis on the impact that this technique has on biophysics, biochemistry and nanoscience. Various lens-based optical techniques, starting from conventional optical microscopy to more advanced methods, such as phase-contrast, fluorescence, confocal and electron microscopy are based on the exploiting of lenses to reproduce an image of the target object. The development of these techniques revolutionized many of scientific fields, especially biology, chemistry, medicine and physical sciences. Nowadays new methods of imaging have been appeared, among which the coherent diffraction imaging deserves a special attention, as one of the most promising methods of high-quality imaging of complex objects, including the imaging on the nanometre length scale. Coherent diffraction imaging (CDI) is a modern approach of 2-dimensional and 3-dimensional reconstruction of an object’s image on the basis of its diffraction pattern, which is recorded as a result of illumination of the object by a coherent beam of x-rays, electrons or protons and subsequent backscattered reflection. The collected diffraction pattern is measured and used for obtaining the image via iterative computational algorithms rather than via lenses (see Fig.1). Because of an image of a target object is created without the use of lenses or other optics, the method is also often called â€Å"lensless imaging.† Such technique allows avoiding an excessive aberration and improving a quality of image, increasing its resolution. CDI involves the â€Å"phase problem† related to the loss of the information that describes